Meanwhile, corporate billionaire Edward Cole (Jack Nicholson) never saw a list without a bottom line. He was always too busy making money and building an empire to think about what his deeper needs might be beyond the next big acquisition or cup of gourmet coffee.

Then life delivered an urgent and unexpected wake-up call to both of them. Carter and Edward found themselves sharing a hospital room with plenty of time to think about what might happen next—and about how much of that was in their hands. For all their apparent differences, they soon discovered they had two very important things in common: an unrealized need to come to terms with who they were and the choices they'd made, and a pressing desire to spend the time they had left doing everything they ever wanted to do.

The list wasn't just a mental exercise anymore. It was an agenda.

So, against doctor's orders and all good sense, these two virtual strangers check themselves out of the hospital and hit the road together for the adventure of a lifetime— from the Taj Mahal to the Serengeti, the finest restaurants to the seediest tattoo parlors, the cockpit of vintage race cars to the open door of a prop plane—with just a sheet of paper and their passion for life to guide them.

Adding and crossing items off their list while taking in the grandeur and beauty of the world, they will grapple with the difficult questions and the even more difficult answers that plague all of us. And, without even realizing it, become true friends. With humor, insight, heart…and a fair amount of attitude.